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More GMO-bashing, but as usual the other side gets short shrift in media

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A French study reporting that mice that ate genetically modified corn sprayed with glyphosate — or drank water with glyphosate levels similar to that in U.S. tap water — were much more likely to die, and to die younger is the latest we’re-all-being-poisoned-the-sky-is-falling scenario from those those who would have agriculture revert to mules and manure — and certainly is nothing new in France, where opposition to GMOs has been a cause célèbre from Day 1.

Thetask force, whose members were drawn from EFSA’s GMO, pesticide and scientific assessment units, has outlined a list of issues about the paper that would need to be resolved before it could be viewed as well-conducted and properly-reported study.

  • The strain of rat used in the two-year study is prone to developing tumors during their life expectancy of approximately two years. This means the observed frequency of tumors is influenced by the natural incidence of tumors typical of this strain, regardless of any treatment. This is neither taken into account nor discussed by the authors.
  • The authors split the rats into 10 treatment sets but established only one control group. This meant there was no appropriate control for four sets — some 40 percent of the animals — all of which were fed GM maize treated or not treated with a herbicide containing glyphosate.
  • The paper has not complied with internationally-recognized standard methods – known as protocols - for setting up and carrying out experiments. Many of these procedures are developed by the OECD (Organisation for Economic Cooperation and Development).
  • For a study of this type, the relevant OECD guideline specifies the need for a minimum of 50 rats per treatment group. Séralini et al used only 10 rodents per treatment set. The low number of animals used is insufficient to distinguish between the incidence of tumors due to chance rather than specific treatment effects.
  • The authors have not stated any objectives, which are the questions a study is designed to answer. Research objectives define crucial factors such as the study design, correct sample size, and the statistical methods used to analyze data — all of which have a direct impact on the reliability of findings.
  • No information is given about the composition of the food given to the rats, how it was stored or details of harmful substances — such as mycotoxins – that it might have contained.
  • It is not possible to properly evaluate the exposure of the rats to the herbicide as intake is not clearly reported. The authors report only the application rate of the herbicide used to spray the plants and the concentration added to the rats’ drinking water but report no details about the volume of the feed or water consumed.
  • The paper does not employ a commonly-used statistical analysis method nor does it state if the method was specified prior to starting the study. The validity of the method used is queried and there are questions over the reporting of tumor incidence. Important data, such as a summary of dropouts and an estimation of unbiased treatment effects have not been included in the paper.
  • Many endpoints — what is measured in the study — have not been reported in the paper. This includes relevant information on lesions, other than tumors, that were observed. EFSA has called on the authors to report all endpoints in the name of openness and transparency.
  • Review of the Séralini et al. (2012) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 <http://www.efsa.europa.eu/en/efsajournal/pub/2910.htm>

Discuss this Blog Entry 7

Anonymous (not verified)
on Oct 12, 2012

There is more wild hyperbole in this editorial than I've seen in any Pro-GMO Labeling argument.

Anonymous (not verified)
on Oct 13, 2012

Absolutely! The same argument is made against scientists that work for Monsanto, et al. Oh my... science, and spin! Common sense will prevail one day when people listen to it instead of being led by others.

Eatfresh (not verified)
on Oct 14, 2012

Another lopsided article from the GMO protaganists & yes Americans are experiencing allergies & diseases at a rate far in excess of other western countries. maybe this has something to do with the 90% of all their crops which are GM.

Why does this industry fight tooth & nail to exclude GM labelling of their frankenfoods??
I think everyone smells a rat, one with lots of tumours.

Anonymous (not verified)
on Oct 15, 2012

Yikes! Tumors? GMO opponents forget that the earth itself has been "genetically modifying" food, animals and plants since time began. Its called evolution and cross-polination. Maybe some folks should have taken more science classes instead of those touchy-feely ones.

Anonymous (not verified)
on Oct 15, 2012

who funds Delta Farm Press? I'm guessing Monsanto and a bunch of other chemical companies. I'd really be interested to know...

Anonymous (not verified)
on Oct 15, 2012

GMO's...new technology...this must be feared. And in 1900 electricity was also feared. This stuff is dangerous, it must not be allowed in our homes! In fact, in one instance a dog was electrocuted every evening to display just how deadly this new technology truly was. Yes, let's ban GMO's, airplanes, cars, cell phones, and electricity. Rural america will be just fine- they can handle organic farming just fine. However, the folks in New York high-rises, and suburbia, USA that pass judgement on modern agriculture...I don't know how well they will fare with the food shortage, or with the request to come hand-weed crops.

Anonymous (not verified)
on Oct 15, 2012

Gasoline is explosive, poisonous and highly carcinogenic. We should probably wear gloves and gas masks, and move our children upwind whenever we stop for gas. Unfortunately, my yard also contains some highly toxic fungi growing on some old logs. My TV shoots out radiation- much like my dentists X-ray machine. When I get sick, I take antibioltic pills which is actually a selective pesticide which kills bacterial cells, but not me. There's some wild deer in my yard, and they might have ticks that carry lymes disease. And I also heard about some e-coli contaminated organic lettuce a few months back. Maybe the intensively tested, USDA and EPA approved ag products are farmers grow aren't so bad?

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